Solid organ fabrication: comparison of decellularization to 3D bioprinting
نویسندگان
چکیده
منابع مشابه
Solid organ fabrication: comparison of decellularization to 3D bioprinting
Solid organ fabrication is an ultimate goal of Regenerative Medicine. Since the introduction of Tissue Engineering in 1993, functional biomaterials, stem cells, tunable microenvironments, and high-resolution imaging technologies have significantly advanced efforts to regenerate in vitro culture or tissue platforms. Relatively simple flat or tubular organs are already in (pre)clinical trials and...
متن کاملTissue engineering by decellularization and 3D bioprinting
1 Pluripotent Stem Cells and Activation of Endogenous Tissue Programs for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), c/ Baldiri Reixac 15-21, 08028 Barcelona, Spain 2 Institute for Bioengineering of Catalonia (IBEC), c/ Baldiri Reixac 15-21, 08028 Barcelona, Spain; University of Barcelona, Spain Nanotechnology Platform, Institute for Bioengineering of Catalonia (IBEC)...
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Hard tissues and organs, including the bones, teeth and cartilage, are the most extensively exploited and rapidly developed areas in regenerative medicine field. One prominent character of hard tissues and organs is that their extracellular matrices mineralize to withstand weight and pressure. Over the last two decades, a wide variety of 3D printing technologies have been adapted to hard tissue...
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Additive manufacturing, commonly referred to as 3D printing, is a technology that builds three-dimensional structures and components layer by layer. Bioprinting is the use of 3D printing technology to fabricate tissue constructs for regenerative medicine from cell-laden bio-inks. 3D printing and bioprinting have huge potential in revolutionizing the field of tissue engineering and regenerative ...
متن کاملOptimized protocol for whole organ decellularization
BACKGROUND The idea of tissue decellularization to gain matrices for tissue engineering is promising. The aim of the present study is to establish a safe and reproducible protocol for solid tissue decellularization that prevents the architecture of the matrix with the inherent vascular network. METHODS The study was performed in rat kidneys which were decellularized by a SDS-based perfusion p...
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ژورنال
عنوان ژورنال: Biomaterials Research
سال: 2016
ISSN: 2055-7124
DOI: 10.1186/s40824-016-0074-2